Alloy Knowledge

Hastelloy C-22 vs. C-276: The Chemical Industry's Toughest Choice

2026-07-14 · 6 min read · TrueGrade Metals engineering team

Hastelloy C-22 vs. C-276: The Chemical Industry's Toughest Choice

Inside chemical plants, the argument over C-22 versus C-276 has been running for thirty years. Both are nickel-chromium-molybdenum alloys with elite corrosion resistance. The difference is six elements of chemistry — and knowing which one your process needs saves either money or equipment.

The chemistry gap in one line

C-276 (UNS N10276): 16% Mo, 4% W, ~15.5% Cr. C-22 (UNS N06022): 13% Mo, 3% W, ~22% Cr. In plain terms — C-276 bets on molybdenum, C-22 bets on chromium.

What that means in the plant

Fabrication and price

Both weld well with matching fillers (ERNiCrMo-4 / ERNiCrMo-10) and both resist weld-zone corrosion better than nearly anything else on the market. C-22 is slightly more resistant to intermetallic precipitation during welding — a real advantage on heavy sections. Pricing is usually within a few percent; availability of the exact product form often decides.

Our honest recommendation

If your medium is a known, stable reducing acid — C-276, the proven answer. If your stream is oxidizing, mixed, or simply not fully characterized — C-22 is the safer default. When a customer sends us an analysis that contains both chlorides and oxidizing ions, we quote C-22.

Shortcut: send the medium, concentration, temperature and any oxidizing species (Fe³⁺, Cu²⁺, dissolved O₂, hypochlorite). We'll confirm the grade in writing within 24 hours — free.
Need material for this application? Send your spec — a named metallurgist replies with a certified quote within 24 hours. Request quote →